I. General information |
Synonyms: |
OCI-LY1 |
Background: |
established from the bone marrow of a 44-year-old man with B-cell non-Hodgkin lymphoma (B-NHL; diffuse large cell), stage 4B at relapse in 1983; assigned to GCB-like lymphoma subtype (germinal center B-cell) |
Species: |
human (Homo sapiens) |
Tissue: |
N/A |
Disease: |
B cell lymphoma |
Gender: |
N/A |
Morphology: |
small round to polymorph cells growing singly in suspension; |
Growth Mode: |
N/A |
Doubling Time: |
ca. 50-60 hours |
DNA Profile: |
N/A
Cobioer’s Cell Line Authentication Service |
Culture Medium: |
IMDM+20%FBS
OCI-LY1完全培養(yǎng)基,# CBP60557M
We strongly suggest to purchase the complete medium from Cobioer.
|
Cryopreservation medium: |
90%FBS+10%DMSO |
Mycoplasma: |
negative in microbiological culture, PCR assays |
Immunology: |
CD3 -, CD10 +, CD13 -, CD19 +, CD20 +, CD34 -, CD37 +, CD38 +, CD80 +, CD138 -, HLA-DR -, sm/cyIgG -, sm/cyIgM +, sm/cykappa +, sm/cylambda -; image |
Fingerprint: |
fluorescent nonaplex PCR of short tandem repeat markers revealed a unique STR DNA profile |
Species: |
N/A |
Cytogenetics: |
human flat-moded hyperdiploid karyotype with 6% polyploidy; 47(41-48)<2n>XY, +7, der(4)t(4;7)(p14;q22), der(7)t(4;7)(p14;p14)del(7)(q22), der(8)t(8;13)(p13;q13), der(8)t(8;8)(p22;q11), der(10)t(10;14)(p14;q32)t(14;11)(q32;q24), der(11)t(11;14)(q24;q32)t(14;18)(q32;q21), del(13)(q31), t(14;18)(q32;q21), der(18)t(3;18)(q24;q21)t(18;18)(p12;q21); carries t(14;18) rearrangements, some cryptic, effecting juxtaposition of IGH with BCL2; resembles published karyotype |
Virus |
PCR: EBV -, HBV -, HCV -, HIV-1 -, HIV-2 -, HTLV-I/-II -, MLV - |
Comments: |
For more information, please contact Cobioer (4008-750-250). |